G. Gordon Gibson, Paul Skett «Introduction to Drug Metabolism (3rd Edition)»Publisher: Nelson Thornes Edition: 2001 ISBN: 0748760113 PDF 256 pages 4,29 MbKey Topics
Optimal ADME properties of a drug candidate.
Common biotransformation reactions and enzymes. Application examples.
Optimization of lead compounds from the drug metabolism perspective.
Assessment and minimization of structural liabilities associated with drug metabolism.
Typical drug metabolism experiments for drug discovery and development.
Regulatory consideration and PhRMA perspective on drug metabolism (including MIST).
Optimal ADME properties of a drug candidate.
Common biotransformation reactions and enzymes. Application examples.
Optimization of lead compounds from the drug metabolism perspective.
Assessment and minimization of structural liabilities associated with drug metabolism.
Typical drug metabolism experiments for drug discovery and development.
Regulatory consideration and PhRMA perspective on drug metabolism (including MIST).
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